Integrins α v β 3 and α v β 5 as prognostic, diagnostic, and therapeutic targets in gastric cancer

Conclusion The expression of αvβ3 and αvβ5 in at least one tumor component in all GC samples is an interesting new result that should form a basis for further investigations; for example, regarding selective integrin antagonists and the value of αvβ3 and αvβ5 as putative prognostic biomarkers. Moreover, both markers might be helpful in the routine classification of GC subtypes.
Source: Gastric Cancer - Category: Gastroenterology Source Type: research