Possible mechanisms mediating apoptosis of bronchial epithelial cells in chronic obstructive pulmonary disease - A next-generation sequencing approach.

CONCLUSION: Our findings suggest PI3K-Akt signaling pathway plays an important role in COPD. We observed altered expression of apoptosis and cell proliferation-related genes that might contribute to the pathogenesis of COPD.
PMID: 30115538 [PubMed - as supplied by publisher]

Source: Pathology, Research and Practice - August 7, 2018 Category: Pathology Authors: Tsai MJ, Chang WA, Jian SF, Chang KF, Sheu CC, Kuo PL Tags: Pathol Res Pract Source Type: research