Psychosocial outcomes in cancer ‐bereaved children and adolescents – A systematic review.
Psycho-Oncology,Volume 0, Issue ja, -Not available-.
Marijuana legalization is in motion: step by step, state by state. Counting Washington, where I live, twelve states have already passed recreational marijuana legislation. At least seven more states, including New York and Minnesota, both traditionally liberal states, are slated for similar legalization in 2019. While stopping the weed train is unlikely (there are profits to be made in this new frontier), ensuring that its brakes and safety protocols are in working order is imperative. Protections for our most vulnerable populations — adolescents, young adults, and people with mental illness issues — ough...
Conditions: Brain Tumor; Brain Tumor, Recurrent; Brain Tumor, Refractory; Brain Tumor, Pediatric; Medulloblastoma; Medulloblastoma Recurrent; Medulloblastoma, Non-WNT/Non-SHH; Medulloblastoma, Non-WNT/Non-SHH, Group 3; Medulloblastoma, Non-WNT/Non-SHH, Group 4; Brai n Cancer; CNS Cancer; CNS Tumor; CNS Neoplasm Interventions: Drug: Prexasertib; Drug: Cyclophosphamide; Drug: Gemcitabine; Biological:...
Conditions: Cardiometabolic Dysregulation; Young Adult Cancer; Adolescent Cancer; Body Composition Intervention: Other: Exercise Sponsor: University of Southern California Not yet recruiting
Cancer and symptom experiences of adolescents and young adults (AYAs) with cancer can be highly variable, creating challenges for clinicians and researchers who seek to optimize AYAs ’ health outcomes. Understanding the heuristics AYAs use to designate priority symptoms can provide insight into the meaning they assign to their symptoms and self-management behaviors.
ConclusionIncreased cytotoxicity of NK cells against NPC cells and increased serum levels of biologically active TRAIL in patients treated with IFN β could be a means to eliminate micrometastatic disease and explain the low systemic relapse rate in this patient group.
In conclusion, we show here that sEVs are responsible for mediating paracrine senescence and speculate that they could be involved in inducing bystander senescence during therapy-induced senescence or aging. In fact, when compared to soluble factors, sEVs have different biophysical and biochemical properties as they have a longer lifespan than do soluble factors and they are more resistant to protease degradation. The idea that blocking sEV secretion could be a potential therapeutic approach to alleviate senescence "spreading" during chemotherapy-induced senescence or in aging tissues presents itself as a very at...
Condition: HPV-associated Cancer Intervention: Behavioral: HPV app intervention Sponsors: University of Minnesota - Clinical and Translational Science Institute; Centers for Disease Control and Prevention Recruiting
CONCLUSIONS: Evaluating 25 years of OGCT incidence data, the highest incidence rates and largest increases in incidence were seen in Eastern Asia. Future studies should focus on etiologic features that may account for geographic variation and increases in incidence of OGCT. PMID: 31303255 [PubMed - as supplied by publisher]