Cardiac transplantation from non-viremic hepatitis C donors

Hepatitis C (HCV) donors are rarely used for cardiac transplantation due to historically poor outcomes. In 2015, nucleic acid testing (NAT) for viral load was added to the routine work-up of organ donors, allowing for the distinction between subjects who remain viremic (HCV Ab+/NAT+) and those who have cleared HCV and are no longer viremic (HCV Ab+/NAT –). The American Society of Transplantation recently recommended that HCV Ab+/NAT– donors be considered non-infectious and safe for transplantation.

Source: The Journal of Heart and Lung Transplantation - August 17, 2018 Category: Transplant Surgery Authors: Snehal R. Patel, Shivank Madan, Omar Saeed, Daniel B. Sims, J. Julia Shin, Cecilia Nucci, Edward Borukhov, Doctor Y. Goldstein, William Jakobleff, Stephen Forest, Sasa Vukelic, Sandhya Murthy, John Reinus, Yoram Puius, Daniel J. Goldstein, Ulrich P. Jorde Tags: ORIGINAL CLINICAL SCIENCE Source Type: research