Insights from the sequence similarity of Zika virus proteins with the Human nerve proteins.
This study found similarities in the Zika V proteins and human nerve tissue proteins. 63 human nerve proteins were screened for similarities with the Zika V of which Neuromodulin, Nestin, Galanin, Bombesin, Calcium-binding protein were found to have similarities to the Zika V poly protein C at different sequence regions. These sequence similarities could be significant in regulating pathogenic interactions/autoimmunity, as Polyprotein C is known to be a virulent factor.
PMID: 30108415 [PubMed]
Source: Bioinformation - Category: Bioinformatics Authors: Marsakatla P, Suneetha S, Lee J, Swaminathan PD, Vasudevan L, Supriya R, Suneetha LM Tags: Bioinformation Source Type: research