Explaining urokinase type plasminogen activator inhibition by amino-5-hydroxybenzimidazole and two naphthamidine-based compounds through quantum biochemistry

Phys. Chem. Chem. Phys., 2018, Accepted Manuscript DOI: 10.1039/C8CP04315A, PaperChristian Solis-Calero, Geancarlo Zanatta, Cl áudia Pessoa, Hernandes Faustino Carvalho, Valder Nogueira Freire Urokinase plasminogen activator (uPA) is a biomarker and therapeutic target for several cancer types whose inhibition has been shown to slow tumor growth and metastasis. In this work, crystallographic data... The content of this RSS Feed (c) The Royal Society of Chemistry
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