[ASAP] Synergistic Multiresidue Substitutions of a Macrocyclic c[Pro-Arg-Phe-Phe-Asn-Ala-Phe- < sc > d < /sc > Pro] Agouti-Related Protein (AGRP) Scaffold Yield Potent and > 600-Fold MC4R versus MC3R Selective Melanocortin Receptor Antagonists

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.8b00684

Source: Journal of Medicinal Chemistry - August 16, 2018 Category: Chemistry Authors: Katlyn A. Fleming, Katie T. Freeman, Mark D. Ericson, Carrie Haskell-Luevano Source Type: research