Uric Acid as a Predictor of Immunoglobulin A Nephropathy Progression: A Cohort Study of 1965 Cases.

CONCLUSIONS: SUA level may be positively associated with the progression of IgAN. It was noticeable that the association of hyperuricemia with IgAN progression was less significant in patients with elder age, lower eGFR, or tubular atrophy/interstitial fibrosis, which may be due to some more confounders in association with the IgA progression in these patients. Future prospective studies are warranted to confirm these findings and to investigate the underlying mechanisms.
PMID: 30110674 [PubMed - as supplied by publisher]

Source: American Journal of Nephrology - August 15, 2018 Category: Urology & Nephrology Authors: Zhu B, Yu DR, Lv JC, Lin Y, Li Q, Yin JZ, Du YY, Tang XL, Mao LC, Li QF, Sun Y, Liu L, Li XF, Fei D, Wei XY, Zhu CF, Cheng XX, Chen HY, Wang YJ Tags: Am J Nephrol Source Type: research