Obesity, infertility and oxidative stress in mouse egg cells
(American Society for Biochemistry and Molecular Biology) Proteomic analysis of oocytes from obese mice showed changes in a protein that promotes antioxidant production and may alter meiotic spindles.
Authors: Macut D, Milutinović DV, Rašić-Marković A, Nestorov J, Bjekić-Macut J, Stanojlović O Abstract Over the last decade, huge achievements have been made in the fields of neurophysiology, molecular endocrinology, and biochemistry, as well as in the successful translation of clinical research into diseases into clinical practice. As regards female reproduction, most of the advances made in this area were achieved in gonadal axis regulation, regulation of behavior through sex steroids, reproductive genetics, preservation of ovarian reproductive function, steroid profiling, and metabolic and overall re...
igi L Abstract It is universally accepted that lifestyle interventions are the first step towards a good overall, reproductive and sexual health. Cessation of unhealthy habits, such as tobacco, alcohol and drug use, poor nutrition and sedentary behavior, is suggested in order to preserve/improve fertility in humans. However, the possible risks of physical exercise per se or sports on male fertility are less known. Being "fit" does not only improve the sense of well-being, but also has beneficial effects on general health: in fact physical exercise is by all means a low-cost, high-efficacy method for prev...
Abstract Polycystic ovary syndrome (PCOS) is the most common metabolic and endocrine disorder in women, leading to infertility. However, there is no general agreement concerning how to diagnose and treat PCOS. The Rotterdam consensus statement from the European Society of Human Reproduction and Embryology/American Society for Reproductive Medicine, the Chinese diagnostic criteria and consensus statement, and the clinical practice guideline from the Endocrine Society in the USA are widely recognized. Guidance has been provided for clinical practice based on a comparative analysis of the above three practice guideli...
(MedPage Today) -- News and commentary from the endocrinology world
[Guardian] Experts have raised fresh alarm that more men could become infertile due to huge drop in sperm quality caused by rising pollution, junk food, obesity, smoking, exposure to plastics and lack of exercise.
Conclusion: Heat stimulation by M-RF treatment induced upregulation of UCP1 and FGF21 expression in serum and/or WATs, which was correlated with reduced total body and WAT weight gain in DIO mice. PMID: 30275865 [PubMed]
CONCLUSION: The compiled results indicate that despite the multifactorial etiology of sexual/reproductive dysfunction, nutritional factors may affect the sexual and reproductive health in both men and women. However, it is necessary further studies to clarify this association, and simultaneously improve the approach and treatment of patients with sexual and/or reproductive problems. PMID: 30255750 [PubMed - as supplied by publisher]
Abstract OBJECTIVE: The aim of the present study was to investigate the changes in serum progranulin and sex hormone levels in infertile women with obesity. MATERIALS AND METHOD: A total of 171 infertile women who have fertility desire were included in this cross-sectional study. The initial assessment included the measurements of weight, height, waist circumference and hip circumference to calculate body mass index (BMI), and waist/hip ratio. All participants were categorized into two groups in accordance with BMI as a control group (