Does normal substantia nigra echogenicity make a difference in Parkinson ’s disease diagnosis? A real clinical practice follow-up study

ConclusionsIn our sample of patients with suspected PD, SN hyperechogenicity predicted PD diagnosis in the long term with a high odds ratio. Conversely, a baseline normal SN echogenicity was associated with a poorer response to PD therapy and change to a different diagnosis from PD. Normal SN appears to be a caveat for clinicians to check for atypical parkinsonism features during follow-up.

http://link.springer.com/10.1007/s00415-018-9006-5

Source: Journal of Neurology - August 16, 2018 Category: Neurology Source Type: research