Active cushing syndrome patients have increased ectopic fat deposition and bone marrow fat content compared to cured patients and healthy subjects: a pilot 1H-MRS study.

CONCLUSIONS: Accumulation of BMF is induced by hypercortisolism. In remission patients BMF reached values of controls. Further studies are needed to determine whether this increase in marrow adiposity in CS is associated with bone loss.
PMID: 30108093 [PubMed - as supplied by publisher]

Source: European Journal of Endocrinology - August 14, 2018 Category: Endocrinology Authors: Maurice F, Dutour A, Vincentelli C, Abdesselam I, Bernard M, Dufour H, Le Fur Y, Graillon T, Kober F, Cristofari P, Jouve E, Pini L, Fernandez R, Chagnaud C, Brue T, Castinetti F, Gaborit B Tags: Eur J Endocrinol Source Type: research