BPI-ANCA in chronic obstructive pulmonary disease with pulmonary Pseudomonas aeruginosa colonization: a potentially novel indicator for poor prognosis.

BPI-ANCA in chronic obstructive pulmonary disease with pulmonary Pseudomonas aeruginosa colonization: a potentially novel indicator for poor prognosis. Br J Biomed Sci. 2018 Aug 14; Authors: Tian Y, Zeng T, Tan L, Wu Y, Yu J, Huang J, Pei Z PMID: 30105943 [PubMed - as supplied by publisher]
Source: British Journal of Biomedical Science - Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

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Chronic obstructive pulmonary disease (COPD) is one of the major public health problems worldwide. Despite an increasing burden of COPD in the world, it is often a neglected disease in low income countries and...
Source: BMC Pulmonary Medicine - Category: Respiratory Medicine Authors: Tags: Research article Source Type: research
Publication date: Available online 15 October 2019Source: Pharmacology &TherapeuticsAuthor(s): Edward D. Chan, Michael M. Chan, Mallory M. Chan, Paul E. MarikAbstractGlucocorticoids (GC) in all its various forms and formulations are likely one of the most commonly used pharmacologic agents in medicine. Their use can be profoundly therapeutic but are also associated with a myriad of acute and chronic side effects. It is fairly well-accepted in the medical community that GC can be life-saving when used in critically ill patients with severe exacerbations of asthma and chronic obstructive pulmonary disease, HIV-associated...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Conclusions Our sequential strategy, using sputum cytology/cytometry to select high-risk individuals for AFB and LDCT, did not lead to a clear stage shift and did not improve the efficiency of lung cancer screening.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung cancer Original Articles: Lung cancer Source Type: research
We read with great interest the well-conducted clinical trial on C-reactive protein (CRP)-guided antibiotic treatment in admitted patients with acute exacerbations of COPD by Prins et al. [1]. This is a study showing that the use of CRP can potentially assist clinicians in making more prudent use of antibiotics in patients with severe exacerbations, as has also been found in the primary care setting [2]. One of the striking results is, however, the disturbingly high rate of treatment failure observed of approximately 24% at 10 days and 45% at 30 days, as pointed out in the accompanying editorial [3], and consiste...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Correspondence Source Type: research
AbstractPurpose of ReviewThis review focuses on the implementation of genomic discoveries associated with smoking behaviors and smoking-related illnesses to improve prevention efforts and smoking cessation.Recent FindingsLarge-scale studies have discovered genomic variation that contributes to smoking heaviness and smoking cessation. Variation in theα5 nicotinic acetylcholine receptor subunit (CHRNA5) and the primary nicotine metabolizing gene (CYP2A6) strongly contribute to smoking behaviors, lung cancer, and chronic obstructive pulmonary disease. The analytic and clinical validity of these genes is clearly establis...
Source: Current Epidemiology Reports - Category: Epidemiology Source Type: research
AbstractThis systematic review aimed to synthesise multimorbidity profiling literature to identify replicable and clinically meaningful groupings of multimorbidity. We searched six electronic databases (Medline, EMBASE, PsycINFO, CINAHL, Scopus, and Web of Science) for articles reporting multimorbidity profiles. The identified profiles were synthesised with multidimensional scaling, stratified by type of statistical analysis used in the derivation of profiles. The 51 studies that met inclusion criteria reported results of 98 separate analyses of multimorbidity profiling, with a total of 407 multimorbidity profiles identifi...
Source: European Journal of Epidemiology - Category: Epidemiology Source Type: research
CONCLUSION: Workplaces can be areas for the prevention and cessation of smoking. PMID: 31611028 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
Authors: Yelgeç NS, Karataş MB, Karabay CY, Çanga Y, Şimşek B, Çalık AN, Emre A Abstract Background: Lead aVR provides prognostic information in various settings for patients with cardiovascular diseases. The present study aimed to investigate the prognostic value of a positive T wave in lead aVR (TaVR) for patients with acute pulmonary embolism (APE). Methods: We screened a total of 412 consecutive patients who were hospitalised with a diagnosis of APE between 2008 and 2018. We investigated electrocardiograms (ECGs) for the presence of a positive TaVR and classified other abnormal ECG find...
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
evilbooyaa said: In fairness - I thought I would go into IM and end up in Cards/GI when I was in the first 2 years of med school. This was after exposure to Rad Onc. Then I rotated through IM as a 3rd year medical student, realized I would have to do 3 years of caring about CHF and COPD and DM and all those other IM things and noped the hell on out of there. It was a process of elimination for me in regards to what I ended up in. In regards to the bolded... Click to expand... Med oncs are the lynchpins of oncology and radiation and surgery is just one of their tools to fight disease
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Radiation Oncology Source Type: forums
Authors: Cruz FF, Rocco PRM Abstract Introduction: Mesenchymal stem/stromal cells (MSCs) have been shown to improve lung function and survival in chronic inflammatory lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), pulmonary arterial hypertension (PAH), and silicosis. Areas covered: This review covers rationale for the use of MSC therapy, along with preclinical studies and clinical trials with MSC therapy in chronic lung diseases. Expert opinion: MSC therapy holds promise for the treatment of chronic lung diseases, mainly when administered at early...
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
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