Costimulatory checkpoint SLAMF8 is an independent prognosis factor in glioma.

CONCLUSION: Our study highlighted the important role of SLAMF8 in malignancy progression, shortened survival, and immune disorders. Further research on SLAMF8 in immunosuppression and inflammation response to glioma cells could aid immunotherapy for glioma.
PMID: 30105842 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - August 13, 2018 Category: Neuroscience Authors: Zou CY, Guan GF, Zhu C, Liu TQ, Guo Q, Cheng W, Wu AH Tags: CNS Neurosci Ther Source Type: research