Sclerostin and its significance for children and adolescents with type 1 diabetes mellitus (T1D)

Recent studies have shown that sclerostin, which is a negative regulator of bone formation, could play an important role in the crosstalk between bone and glucose metabolism. The role of sclerostin and its link with glucose homeostasis in type 1 diabetes mellitus (T1D) has not been yet studied extensively in children. The aim of this study was to assess sclerostin and its relationship between other bone and fat related factors as well as glucose metabolism in children and adolescents with T1D in comparison to their healthy peers.
Source: Bone - Category: Orthopaedics Authors: Tags: Full Length Article Source Type: research