Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway

Org. Biomol. Chem., 2018, Accepted Manuscript DOI: 10.1039/C8OB01565A, PaperSean Newmister, Stelamar Romminger, Jennifer J. Schmidt, Janet L L Smith, Robert Michael Williams, Roberto Berlinck, David H. Sherman Antimicrobial and anti-proliferative meleagrin and oxaline are roquefortine C-derived alkaloids produced by fungi of the genus Penicillium. Tandem O-methylations complete the biosynthesis of oxaline from glandicoline B through meleagrin. Currently,... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research