IJERPH, Vol. 15, Pages 1755: Correlation between Non-Polio Acute Flaccid Paralysis Rates with Pulse Polio Frequency in India

IJERPH, Vol. 15, Pages 1755: Correlation between Non-Polio Acute Flaccid Paralysis Rates with Pulse Polio Frequency in India International Journal of Environmental Research and Public Health doi: 10.3390/ijerph15081755 Authors: Rachana Dhiman Sandeep C. Prakash V. Sreenivas Jacob Puliyel The last case of polio from India was reported in 2011. That year, the non-polio acute flaccid paralysis (NPAFP) rate in India was 13.35/100,000, where the expected rate is 1–2/100,000. A previous study of data from 2000 to 2010 has detailed the NPAFP rate in a state correlated with the pulse polio rounds conducted there, and the strongest correlation with the NPAFP rate was found when the number of doses from the previous 4 years were used. However, a simple association being found with regression analysis does not prove a causal relationship. After publication of those findings, as the threat of polio had lessened, the number of rounds of OPV administration was brought down. The present study has been done to look at data till the end of 2017, to see if the incidence of NPAFP declined with this reduction in polio immunization rounds. We used polio surveillance data acquired by the Government of India from 2000–2017. Correlation of the NAFP rate to the number of polio rounds in the state was examined, and the cumulative effect of polio doses administered in previous years was sought. NPAFP rate correlated with the OPV pulse polio rounds in that year ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research