Stem cells for lupus nephritis: a concise review of current knowledge.

Stem cells for lupus nephritis: a concise review of current knowledge.
Lupus. 2018 Aug 12;:961203318793206
Authors: Sattwika PD, Mustafa R, Paramaiswari A, Herningtyas EH
Abstract
Lupus nephritis (LN), a common manifestation of systemic lupus erythematosus (SLE), accounts for significant morbidity and mortality in SLE patients. Since the available standard therapies and biologic agents for LN are yet to achieve the desired response and have considerable secondary effects, stem cell therapy has now emerged as a new approach. This therapy involves the transplantation of hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs). Our current review will highlight the progress of stem cell therapy for LN, along with the challenges encountered and the future direction of this approach.
PMID: 30099942 [PubMed - as supplied by publisher]

Source: Lupus - August 12, 2018 Category: Rheumatology Authors: Sattwika PD, Mustafa R, Paramaiswari A, Herningtyas EH Tags: Lupus Source Type: research