Trajectories of body fatness from age 5 to 60 y and plasma biomarker concentrations of the insulin-insulin-like growth factor system.

Conclusions: Adiposity across the life span was associated with higher C-peptide and lower IGFBP-1 concentrations in adulthood. The associations were largely driven by attained adiposity and, to a lesser extent, weight gain in early-middle adulthood. This trial was registered at www.clinicaltrials.gov as NCT03419455. PMID: 30101328 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30101328?dopt=Abstract

Source: Am J Clin Nutr - August 1, 2018 Category: Nutrition Authors: Kværner AS, Hang D, Giovannucci EL, Willett WC, Chan AT, Song M Tags: Am J Clin Nutr Source Type: research