Toward a Very Brief Quality of Life Enjoyment and Satisfaction Questionnaire

Changes in the nine criterion symptoms of major depressive disorder (MDD) are the primary metric to gauge the efficacy of antidepressant medications and other treatments. Symptomatic remission remains the preferred outcome of acute-phase treatment (Bauer et al., 2013; Cleare et al., 2015; Gelenberg et al., 2010; Kennedy et al., 2016; Rush et al., 2006b) (because remission is associated with a better long-term prognosis (lower risk of relapse) (Rush et al., 2006c) and better day-to-day function (Bauer et al., 2013; Miller et al., 1998; Trivedi et al., 2009) than either response (>50% reduction from baseline) without remission or non-response.

Source: Journal of Affective Disorders - August 14, 2018 Category: Neurology Authors: A. John Rush, Charles C. South, Manish K. Jha, Bruce D. Grannemann, Madhukar H. Trivedi Tags: Research paper Source Type: research