Five-month-old receives heart-lung transplant an is youngest in 10 years to undergo the surgery
Jack Palmer, of Kansas City, Missouri, became the 20th infant under a year old to undergo a heart-lung transplant after he was born in January with a congenital heart defect.
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By ANISH KOKA MD The message comes in over the office slack line at 1:05 pm. There are four patients in rooms, one new, 3 patients in the waiting room. Really, not an ideal time to deal with this particular message. “Kathy the home care nurse for Mrs. C called and said her weight yesterday was 185, today it is 194, she has +4 pitting edema, heart rate 120, BP 140/70 standing, 120/64 sitting” I know Mrs. C well. She has severe COPD from smoking for 45 of the last 55 years. Every breath looks like an effort because it is. The worst part of it all is that Mrs. C just returned home from the hospital just days...
Left Ventricular Assist Device (LVAD) support is a well established therapy for treatment of adult patients with end-stage heart failure (ESHF),1 in whom several types of devices varying in location, pump size, mechanics, and design are ‘officially’ available in the market. On the contrary, children with ESHF refractory to conventional therapy have much fewer ‘official’ and well-accepted options which require a continuous hospitalization and hinder patients’ mobility.2-13
68 year old man from Bangalore, got a new life as he underwent heart and lungs transplant at Narayana Health City, Bangalore. The donor is a 24yr old male fr...
The risk of infection following heart transplantation is highest within the first year and represents the leading cause of early mortality. In this cohort of patients enrolled in the Outcomes AlloMap Registry (OAR), we sought to describe infection episodes (IEp) resulting in hospitalization, in early (
Pulmonary cuff dysfunction, either due to pulmonary vein obstruction, pulmonary vein stenosis, or pulmonary vein thrombosis is an uncommon, yet serious complication after lung transplantation. While there have been numerous reports of its occurrence, there is little consensus regarding the hemodynamic parameters associated with its presentation and diagnostic considerations. This systematic review summarizes the evidence surrounding pulmonary cuff dysfunction after lung transplantation surgery and empirically analyzes its implications.
Some literature exists potentially linking proliferation signal inhibitors (PSIs) to venous thromboembolism (VTE). We sought to determine the impact of PSI on development of VTE in heart transplant (HT) patients while controlling for other risk factors.
Vasoplegic syndrome (VS) is a type of vasodilatory shock defined by a constellation of a high cardiac output state, low systemic vascular resistance (SVR), low filling pressures, and low mean arterial pressure (MAP) despite high-dose vasoconstrictors. It is a well-known phenomenon following cardiopulmonary bypass (CPB), with a reported incidence of 8-10%,1 and is more common following left ventricular assist device (LVAD) placement (42%).2 VS is associated with significant morbidity and a mortality rate ranging from 16-27%.
It is with great interest we read the case report entitled “Lung transplantation in a patient with Niemann-Pick disease” by Mannem H et al.1 Unfortunately, the patient died within 30 days of lung transplantation from acute lung injury due to pro-inflammatory state caused by flooded recipient-derived abnormal macrophage in the lungs. The authors conclude d that transplanting patients with orphan lung condition like Niemann-Pick Disease carries a higher risk of complications since the effect of the underlying disease on the post-operative course is difficult to predict.
We report the case of a 65-year-old male with non-ischemic cardiomyopathy requiring left ventricular assist device (LVAD) implantation in 2014. He developed a Staphylococcus aureus (SA) device infection complicated by sternal osteomyelitis and bacteremia leading to multiple hospitalizations, surgical debridements, and prolonged intravenous (IV) antibiotics (Supplement Table 1). He was deemed ineligible for heart transplant because of ongoing infection and presented to our center for a second opinion.