Toll-like receptor-4 deficiency alleviates chronic intermittent hypoxia-induced renal injury, inflammation, and fibrosis.

CONCLUSIONS: Our data suggest that TLR4 plays a vital role in CIH-induced renal injury, inflammation and fibrosis, and inhibition of TLR4 probably provides a therapeutic potential for CIH-induced kidney damage.
PMID: 30099700 [PubMed - as supplied by publisher]

Source: Sleep and Breathing - August 11, 2018 Category: Sleep Medicine Authors: Zhang Y, Su X, Zou F, Xu T, Pan P, Hu C Tags: Sleep Breath Source Type: research