Salivary exosomes as potential biomarkers in cancer

The intercellular communication between cancer cells and surrounding stromal cells is crucial for modulating tumorigenesis as well as for the development and progression of tumour metastasis. Understanding the molecular mechanisms involved in this cellular cross-talk provides new insights into the identification of valuable biomarkers as well as therapeutic targets that can stop tumour progression [1]. Cell to cell communication by extracellular vesicles is a burgeoning area of research and these are considered key players in mediating communication between tumour cells and healthy, normal cells [2].
Source: Oral Oncology - Category: Cancer & Oncology Authors: Tags: Review Source Type: research