The importance of homocysteine levels in the prognosis of patients with chronic renal disease and in hemodialysis patients

Conclusion: Hcy could be an important biomarker of renal disease progression mainly in hemodialysis patients. We emphasize the importance of normalizing plasma levels of this amino acid to ensure a better prognosis in kidney disease.RESUMO Introdu ção: A homocisteína (Hcy) é um dos metabólitos da metionina (Met), um aminoácido essencial proveniente da dieta. Existe uma estreita relação entre os altos níveis plasmáticos de Hcy e o declínio da função renal. A Hcy plasmática e urinária tem sido alvo de estudos como um biomarcador capaz de sinalizar o prognóstico em doentes renais e em pacientes em hemodiálise. Esta revisão avalia os principais estudos que buscaram correlacionar a Hcy e o prognóstico da doença renal e descreve os tratamentos propostos para a redução dos níveis plasmáticos de Hcy nesses pacientes. Co nclusão: A Hcy pode ser um biomarcador da progressão na doença renal, principalmente em pacientes hemodialíticos. Ressaltamos a importância da normalização dos níveis plasmáticos desse aminoácido para garantir um melhor prognóstico na doença renal.
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - Category: Pathology Source Type: research

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Condition:   End-stage Renal Disease (ESRD) Interventions:   Procedure: Repeated cannulation Buttonhole.;   Procedure: Single cannulation Buttonhole. Sponsors:   Hospital of South West Jutland;   Kolding Sygehus Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Hypertension in Dialysis Patients;   Fluid Overload in Dialysis Patients Interventions:   Other: Sodium Restricted Meals;   Other: Control Sponsor:   Tufts Medical Center Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The original version of this article unfortunately contained a mistake. The name of Vimal Chadha was presented incorrectly. The corrected author list is given above.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
ConclusionsRenal biopsies, while not commonly performed in children with SCD, were universally abnormal. Outcomes were poor in this cohort of patients despite a variety of post-biopsy interventions. Effective early intervention to prevent chronic kidney disease (CKD) is needed to reduce morbidity and mortality in children with SCD.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
AbstractBackgroundAccess-related infections are a major cause of morbidity and mortality in haemodialysis patients. Our goal was to decrease the rate of these infections by implementing an intervention and surveillance program.MethodsThis intervention took place in two haemodialysis units (Units A and B) and was a joint effort by the haemodialysis staff and the unit for infection prevention and control. It included reviewing the work methods and work space, observations on compliance with standard precautions and handling of the vascular access, creating a checklist and a designated kit for handling the vascular access and...
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Benil Hafeeq, Jyotish Chalil Gopinathan, Feroz Aziz, Sajith Narayanan, Idrees Velikkalagath, Ismail Naduvileparambil Aboobacker, NA UvaisIndian Journal of Public Health 2019 63(2):157-159 Renal replacement therapy in India is predominantly a private health-care-driven initiative making it an expensive treatment option due to high out-of-pocket expenditures. Moreover, with the rapid increase in the number of chronic kidney disease patients requiring dialysis, hemodialysis units (HDUs) are getting saturated. Community “stand-alone” dialysis centers could be an important alternative to HDUs in meeting the growing...
Source: Indian Journal of Public Health - Category: International Medicine & Public Health Authors: Source Type: research
ConclusionsThe results of the present study suggest that LC has potential in preventing low bone turnover, in comparison to CC, in patients new to HD.
Source: Journal of Bone and Mineral Metabolism - Category: Orthopaedics Source Type: research
AbstractPurposeThe association betweenHelicobacter pylori (HP) infection and duration of dialysis in dialysis patients is conflicting, this meta-analysis was conducted to elucidate the association between duration of dialysis and HP infection status in dialysis patients, and subgroup study was conducted to explore its influencing factors. Furthermore, our study aims to provide advice on the treatment of dialysis patients.MethodsArticles published up to 30 September 2018 were searched from PubMed, Embase, Sinomed, Medline, China Knowledge Resource Integrated Database (CNKI) and Wang fang database. Two researchers independen...
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
The aim of this study was to examine the effect of the application of lavender oil on fatigue and anxiety levels in patients undergoing hemodialysis treatment. This randomized controlled study was conducted with 60 patients (30 patients in intervention group, 30 patients in control group) in a province located in southeastern Turkey. After the patients in both groups were informed about the study, a questionnaire, the Fatigue Severity Scale, and the Beck Anxiety Inventory were applied to the patients. In the intervention group, a statistically significant difference was found between pretest and posttest scores of the Fati...
Source: Holistic Nursing Practice - Category: Nursing Tags: FEATURES Source Type: research
Conditions:   Atrial Fibrillation;   End Stage Renal Failure on Dialysis Interventions:   Drug: Warfarin;   Drug: Apixaban;   Other: No oral anticoagulation Sponsors:   St. Michael's Hospital, Toronto;   Canadian Institutes of Health Research (CIHR) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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