Molecular Reductions in Glucokinase Activity Increase Counter-regulatory Responses to Hypoglycemia in Mice and Humans with Diabetes

ConclusionsOur data suggest that glucokinase in brain and other non β-cell peripheral hypoglycemia sensors is important in glucose homeostasis, allowing the body to detect and respond to a falling blood glucose.Graphical abstract
Source: Molecular Metabolism - Category: Endocrinology Source Type: research