Rational development of synergistic combinations of chemotherapy and molecular targeted agents for colorectal cancer treatment

The irinotecan-induced phosphokinome changes in colorectal cancer (CRC) cells were used to guide the selection of targeted agents to be tested in combination with irinotecan.

Source: BMC Cancer - August 13, 2018 Category: Cancer & Oncology Authors: Diego Tosi, Esther P érez-Gracia, Salima Atis, Nadia Vié, Eve Combès, Mélissa Gabanou, Christel Larbouret, Marta Jarlier, Caroline Mollevi, Adeline Torro, Maguy Del Rio, Pierre Martineau and Céline Gongora Tags: Research article Source Type: research