Evaluation of malaria multiplex/nested PCR performance at low parasite densities and mixed infection in Iran: A country close to malaria elimination.

CONCLUSION: In this study, we showed that microscopic examination of blood smears does not reliably distinguish Plasmodium species in the case of mixed infections. Therefore, it seems that multiplex/nested PCR is a good candidate for examining the presence of malaria parasites in clinically suspected but microscopically negative cases.
PMID: 30096462 [PubMed - as supplied by publisher]

Source: Infection, Genetics and Evolution - August 7, 2018 Category: Genetics & Stem Cells Authors: Mirahmadi H, Shahrakipour A, Mehravaran A, Khorashad AS, Rahmati-Balaghaleh M, Zarean M Tags: Infect Genet Evol Source Type: research