Palliative therapy concepts for pancreatic carcinoma.

[Palliative therapy concepts for pancreatic carcinoma]. Chirurg. 2018 Aug 09;: Authors: Brunner M, Grützmann R, Weber GF Abstract The majority of patients with ductal pancreatic adenocarcinoma are already in a locally advanced or metastatic stage at the time of diagnosis and require palliative therapy. Interventional and operative measures are available for the restoration of biliary outflow in bile duct obstruction and the continuity of the upper intestinal lumen in duodenal or gastric outlet obstruction. In the presence of tumor-related pain, pain therapy according to the World Health Organization (WHO) scheme or a truncus coeliacus blockade, in cachexia a nutritional therapy and in thromboembolic events an anticoagulant therapy are used. An individualized palliative chemotherapy regimen should be selected for each patient, taking into account the patient's general condition and the side effects profile of the chemotherapeutic agents. Radiochemotherapy and local ablative therapies should currently only be used within the framework of studies. A palliative resection is not recommended according to current knowledge. PMID: 30094706 [PubMed - as supplied by publisher]
Source: Der Chirurg - Category: Surgery Authors: Tags: Chirurg Source Type: research

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ConclusionsThis is the first demonstration that the value of pain follows a curvilinear function and is relative to the mean and standard deviation of competing monetary rewards. These new observations significantly contribute to our understanding of how pain is assigned value when making decisions between avoiding pain and obtaining rewards.
Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Underwater communities rely on fast-growing kelp for food and shelter More at https://www.nsf.gov/discoveries/disc_summ.jsp?cntn_id=303988&WT.mc_id=USNSF_1 This is a Research News item.
Source: NSF Discoveries - Category: Science Source Type: research
Source: Risk Management and Healthcare Policy - Category: Health Management Tags: Risk Management and Healthcare Policy Source Type: research
ConclusionNeoadjuvant chemoradiotherapy with and without hyperthermia for retroperitoneal sarcomas is feasible and provided high local control of intermediate- and high-grade sarcoma.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research
This study sought to design and validate a  nomogram capable of predicting outcomes in extensive-stage small-cell lung cancer (ES-SCLC) patients with superior vena cava syndrome (SVCS) based upon the timing of their radiotherapy treatment.MethodsWe retrospectively analyzed data from 175 ES-SCLC patients with SCVS, comparing outcomes between those that underwent upfront thoracic radiotherapy (initial radiotherapy with simultaneous chemotherapy) and those that underwent consolidative thoracic radiotherapy (following 4 –6 cycles of chemotherapy). Significant predictors of patient outcomes were identified using...
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research
ConclusionMagnetic Resonance Image (MRI) linac-based planning for HNC is already feasible with good quality. Generally, an increased number of segments and increasing planning experience are able to provide better results regarding planning quality without significantly prolonging overall treatment time.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research
AbstractA  70-year old male with stage I large cell neuroendocrine carcinoma (LCNEC) of the lung underwent resection of a metachronous 5 cm brain metastasis and received postoperative hypofractionated stereotactic radiotherapy (hfSRT). Five sequential nodular leptomeningeal metastases up to 5.3 cm in di ameter were diagnosed on MRI within 10 months and were treated with SRT. Currently the patient has no evidence of intracranial disease 24 months after last irradiation without chemotherapy or whole brain radiotherapy. This is the first report of sustained complete remission of multiple large lepto me...
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research
The objective of this study was to assess the efficacy and feasibility of neoadjuvant concurrent chemoradiotherapy (cCRT) in selected grade 2–3 patients with limb or trunk wall STS, and to compare this schedule to a  sequential approach combining neoadjuvant chemotherapy and adjuvant radiotherapy.MethodsWe retrospectively included patients who underwent neoadjuvant cCRT at two comprehensive cancer centers from 1992 –2016. We then compared these results to those of patients treated with preoperative chemotherapy and postoperative radiotherapy from a third comprehensive cancer center with a pr...
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research
Contrast-enhanced ultrasound (CEUS) lymphosonography is useful in identifyin...Read more on AuntMinnie.comRelated Reading: AI could help with breast ultrasound workloads How ultrasound can help speed up winemaking DBT can help evaluate cases of focal breast pain POCUS making waves, but questions remain Ultrasound finds swollen glands on patients after COVID-19 vaccine
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Conclusion One of the ways to ensure you lead a happy and quality life is to take good care of your mental health continually. Practicing the habits discussed above will take you a step forward in staying mentally healthy. Do you have any bad mental health habits you struggle with? Can you commit to kicking them to the curb and practicing the above helpful mental health habits? We would appreciate your feedback in the comment section.   Sherry Kimball likes to write articles with advice that help people to improve their lives.  Sherry enjoys researching, discussing, and writing on the topics of ...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: featured happiness psychology habits mental health Source Type: blogs
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