BMI1 drives metastasis of prostate cancer in Caucasian and African-American men and is a potential therapeutic target: hypothesis tested in race-specific models.

CONCLUSION: BMI1, a major driver of metastasis, represents a promising therapeutic target for treating advanced CaP in patients (including those belonging to high-risk group).
PMID: 30087142 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - August 7, 2018 Category: Cancer & Oncology Authors: Ganaie A, Beigh FH, Astone M, Ferrari MG, Maqbool R, Umbreen S, Parray AS, Siddique HR, Hussain T, Murugan P, Morrissey C, Koochekpour S, Deng Y, Konety BR, Hoeppner LH, Saleem M Tags: Clin Cancer Res Source Type: research