RapidBrachyMCTPS: a Monte Carlo-based treatment planning system for brachytherapy applications.

RapidBrachyMCTPS: a Monte Carlo-based treatment planning system for brachytherapy applications. Phys Med Biol. 2018 Aug 10;: Authors: Famulari G, Renaud MA, Poole CM, Evans MDC, Seuntjens J, Enger SA Abstract Despite being considered the gold standard for brachytherapy dosimetry, Monte Carlo (MC) has yet to be implemented into a software for brachytherapy treatment planning. The purpose of this work is to present RapidBrachyMCTPS, a novel treatment planning system (TPS) for brachytherapy applications equipped with a graphical user interface (GUI), optimization tools and a Geant4-based MC dose calculation engine, RapidBrachyMC. Brachytherapy sources and applicators were implemented in RapidBrachyMC and made available to the user via a source and applicator library in the GUI. To benchmark RapidBrachyMC, TG-43 parameters were calculated for the microSelectron v2 (<sup>192</sup>Ir) and SelectSeed (<sup>125</sup>I) source models and were compared against previously validated MC brachytherapy codes. The performance of RapidBrachyMC was evaluated for a prostate HDR case. To assess the accuracy of RapidBrachyMC in a heterogeneous setup, dose distributions with a cylindrical shielded/unshielded applicator were validated against film measurements in a Solid Water<sup>TM</sup> phantom. TG-43 parameters calculated using RapidBrachyMC generally agreed within 1%-2...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research