Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins

The Musashi (MSI) family of RNA-binding proteins is best known for the role in post-transcriptional regulation of target mRNAs. Elevated MSI1 levels in a variety of human cancer are associated with up-regulati...

Source: BMC Cancer - August 10, 2018 Category: Cancer & Oncology Authors: Lan Lan, Hao Liu, Amber R. Smith, Carl Appelman, Jia Yu, Sarah Larsen, Rebecca T. Marquez, Xiaoqing Wu, Frank Y. Liu, Philip Gao, Ragul Gowthaman, John Karanicolas, Roberto N. De Guzman, Steven Rogers, Jeffrey Aub é, Kristi L. Neufeld & hellip; Tags: Research article Source Type: research