Effects of Oncostatin M on Invasion of Primary Trophoblasts under Normoxia and Hypoxia Conditions.

CONCLUSION: OSM might be involved in the invasiveness of extravillous trophoblasts under hypoxia conditions via increasing MMP-2 and MMP-9 enzymatic activities through STAT3 signaling. Increased MMP-9 activity by OSM seems to be more important in primary trophoblasts.
PMID: 30091322 [PubMed - in process]

Source: Yonsei Medical Journal - August 11, 2018 Category: Universities & Medical Training Authors: Wie JH, Ko HS, Choi SK, Park IY, Kim A, Kim HS, Shin JC Tags: Yonsei Med J Source Type: research