Contribution of Volume Overload to Progression of Cardiovascular Diseases in Rat Model of Chronic Kidney Disease.

In conclusion, salt induced volume overload in a rat model of CKD had an adverse cardiovascular outcome and it was associated with inflammatory activation and decrease in renal klotho expression. PMID: 30079760 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30079760?dopt=Abstract

Source: Canadian Journal of Physiology and Pharmacology - August 4, 2018 Category: Drugs & Pharmacology Authors: Mahmoud MM, Shamseldeen A, Rashed LA, Fares AE, Shamaa A, Gharib DM Tags: Can J Physiol Pharmacol Source Type: research