Bladder perivascular epithelioid cell tumors

ConclusionEvolution and prognosis evaluation remain hard and could necessitate a radical surgery. Prognosis criteria for the bladder PEComas have to be clarified.
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research

Related Links:

Condition:   Bladder Cancer Intervention:   Other: Targeted Interventions for Impairments Identified During Geriatric Assessment Sponsor:   UNC Lineberger Comprehensive Cancer Center Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Source: Cancer Management and Research - Category: Cancer & Oncology Tags: Cancer Management and Research Source Type: research
It is now well-recognized that the tumor microenvironment (TME) is not only a key regulator of cancer progression but also plays a crucial role in cancer treatment responses. Recently, several high-profile publications have demonstrated the importance of particular immune parameters and cell types that dictate responsiveness to immunotherapies. With this increased understanding of TME-mediated therapy, approaches that increase therapeutic efficacy by remodeling the TME are actively being pursued. A classic example of this, in practice by urologists for over 40 years, is the manipulation of the bladder microenvironment for ...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
ConclusionsIt was shown that increasing age was not associated with BCG immunotherapy oncological outcomes, or with BCG toxicity in T1HG non-muscle invasive bladder cancer.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
When the number of doses of BCG for high-grade non-muscle invasive bladder cancer was cut, outcomes were inferior in a randomized clinical trial.Medscape Medical News
Source: Medscape Urology Headlines - Category: Urology & Nephrology Tags: Hematology-Oncology News Source Type: news
AbstractObjectiveIntensity-modulated radiation therapy (IMRT) using a volumetric-modulated arc therapy technique may offer dosimetric and clinical benefits compared to the historical standard of care 3D conformal radiotherapy (3D-CRT) in definitive treatment of bladder cancer. We hypothesized that IMRT with CBCT would reduce dose to the rectum, bowel, and bladder compared to 3D-CRT.MethodsWe reviewed nineteen patients treated with maximal transurethral resection of bladder tumor followed by concurrent chemotherapy with IMRT. All patients received 45  Gy to the entire empty bladder followed by 19.8 Gy tumor boost ...
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research
Recent NICE guidance says there is limited evidence for the efficacy of transurethral laser ablation for recurrent non ‐muscle invasive bladder cancer and that ‘special arrangements’ need to be in place if it is to be offered to patients. Here the authors consider the advantages and drawbacks of the treatment.
Source: Trends in Urology and Men's Health - Category: Urology & Nephrology Authors: Tags: NICE guidance Source Type: research
Gallbladder cancer is the most common biliary tract cancer with poor prognosis and wide variation in incidence rates worldwide, being very high in some countries in Latin America and Asia. Treatment of type 2 diabetes with metformin causes a reduction in the incidence of cancer. Till date, there are no reports on the anti-tumor effects of metformin in gall bladder cancer. Therefore, this study evaluated the effects of metformin on the proliferation of human gallbladder adenocarcinoma cells in vitro and in vivo, as well as explored the microRNAs associated with the anti-tumor effects of metformin. Metformin inhibited the pr...
Source: Anti-Cancer Drugs - Category: Cancer & Oncology Tags: Preclinical Reports Source Type: research
AbstractIn the past decades, the roles of carbohydrates in living organisms and their potential use in many fields have been extensively investigated. Sialyl Lewis x (sLex), a member of body carbohydrate, is an inherent blood-type tetrasaccharide on the surface of different cells, the lymphocyte, neutrophil, some T cells, multiple tumor cells and so on. SLex is a common ligand of the three selectins, L-selectin, E-selectin and P-selectin, and plays important roles in multiple physiological phenomenas by interacting with selectins. Under normal physiological conditions, sLex can affect the immune process and fertilization p...
Source: Glycoconjugate Journal - Category: Biochemistry Source Type: research
ConclusionsThis is the first study testing the role of time to Re-TUR in a homogeneous population of patients with high-grade T1 BC who received complete BCG treatment. The study challenged the concept the sooner the Re-TUR the better, since time to Re-TUR did not significantly affect oncological outcomes.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
More News: African Health | Bladder Cancer | Cancer | Cancer & Oncology | Urology & Nephrology | Women