Native chemical ligation at methionine bioisostere norleucine allows for N-terminal chemical protein ligation

Org. Biomol. Chem., 2018, Accepted Manuscript DOI: 10.1039/C8OB01627E, PaperPaul P Geurink, Huib Ovaa, Bo-Tao Xin, Bianca D.M. van Tol The development of γ-thionorleucine (ThioNle) as handle for native chemical ligation-desulfurization is reported here. ThioNle is a new addition to the expanding thiolated amino acid toolbox and serves as methionine... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research