Renal Cell Carcinoma and Myelodysplastic Syndrome Show Epigenetic Association
Hypermethylation has been documented in some myeloid disorders including myelodysplastic syndrome (MDS) and in renal cell carcinoma (RCC). A group at the Mayo Clinic noticed the epigenetic marking patterns between these vastly different conditions and wondered if there was a connection. The group found that there was a strong association.08/09/2018
Peng Wu, Guihao Zhang, Jie Zhao, Jiawei Chen, Yang Chen, Weina Huang, Jialei Zhong, Jiarong Zeng
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN02182A, PaperDan Guo, Zhen-Fei Gan, Lei Jiang, Mao-Feng Cao, Patrice Tano Fato, Mahmoud Elsayed Hafez, Da-Wei Li Leucine aminopeptidase (LAP), an important proteolytic enzyme, is closely associated with diverse physiological and pathological disorders such as liver injury and cancers. Hence, it is imperative to develop an effective... The content of this RSS Feed (c) The Royal Society of Chemistry
[Premium Times] On Saturday 8th December 2018, Janssen, one of the Pharmaceutical Companies of Johnson&Johnson, invited guests to 'More Time For Life!', a one day health and social networking event that aimed to encourage men to be more proactive in taking control of their health in general and prostate health in particular.
U.S. patients with a mental health illness have a considerably higher smoking...Read more on AuntMinnie.comRelated Reading: MRI shows promise for lung cancer screening CT lung cancer screening foiled by low adherence CT lung screening reduces cancer mortality in men by 26% Access to CT lung screening varies by population density CT lung screening may benefit racial minorities most
Radiation therapy software developer RaySearch Laboratories said it will develop...Read more on AuntMinnie.comRelated Reading: RaySearch to unveil new deep-learning software at ASTRO RaySearch signs Canadian cancer center RaySearch, Canon sign collaboration pact RaySearch signs Swedish Cancer Institute RaySearch to highlight software upgrades at AAPM
Is PET or MRI better for detecting tumor recurrence in patients with brain...Read more on AuntMinnie.comRelated Reading: DWI-MRI may be best for indeterminate lung nodules How effective is PET/MRI for rectal cancer? MRI shows promise for lung cancer screening Can whole-body MRI be used in oncologic staging?
The synthetic sibling of an expensive molecule harvested from a tiny seaweed-dwelling animal could lead to next-generation cancer drugs or a functional cure for HIV, an East Bay company believes. Those lofty targets are years in the distance for startup BryoLogyx Inc., but the company said it will expand preclinical testing next year with synthetic bryostatin, eyeing more investor and scientific interest. BryoLogyx bought exclusive rights to synthetic bryostatin and its potential offshoot s from…
Breast cancer survivors may be more likely to experience anxiety, depression, sleep troubles and other mental health issues than women who have not been diagnosed with the disease, a research review suggests.Reuters Health Information
We report updated results of the primary (PFS) and secondary (overall survival [OS] and toxicity) endpoints.Patients and Methods: Between 4/15/2015-1/27/2016, 27 evaluable pts were treated on 28 day cycles with ELO, 10 mg/kg iv weekly for cycles 1-2, q2weeks for cycles 3-6, then 20 mg/kg once monthly for cycles 7+. Pts enrolled after 1/28/2016 (n=57 pts) have received ELO, 10 mg/kg IV weekly for cycles 1-2, and 20 mg/kg on day 1 from cycle 3 until disease progression (PD). LEN has been dosed at 10 mg/day for cycles 1-3, with a dose increase to 15 mg/day at physician discretion starting with cycle 4, in the absence of non-h...
CONCLUSIONS: This study suggests that patients with acromegaly have an increased risk of thyroid cancer and therefore they should undergo regular screening with hormonal and ultrasound evaluation of the thyroid and FNAB when required. PMID: 27685924 [PubMed - as supplied by publisher]