Brain Evolution May Play Role in Mental Illnesses

Illnesses such as schizophrenia and bipolar disorder may be the result of changes in the human brain that took place during evolution, new research suggests.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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Accelerated aging of cognitive networks after psychosis onset may offer the potential for early intervention in patients with schizophrenia or bipolar disorder, new research suggests.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Psychiatry News Source Type: news
We’ve all experienced it – that feeling of smug happiness at another person’s misfortune. From someone slipping on a banana peel to a jerk receiving a dose of instant karma, there’s something satisfying about this strange emotion. Why is that? Are we living in an “Age of Schadenfreude”? Should we feel guilty about feeling it? And for crying out loud, how do we say it in English?  Listen in to find out! Subscribe to Our Show! And Remember to Review Us! About Our Guest Dr. Tiffany Watt Smith is a cultural historian and author of The Book of Hu...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Happiness Psychology The Psych Central Show Emotion Gabe Howard schadenfreude Vincent M. Wales Source Type: blogs
Publication date: Available online 18 February 2019Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Benjamín Cea-Cañas, Rodrigo de Luis, Alba Lubeiro, Javier Gomez-Pilar, Eva Sotelo, Pilar del Valle, Marta Gómez-García, Adrián Alonso-Sánchez, Vicente MolinaAbstractPrevious studies based on graph theory parameters applied to diffusion tensor imaging support an alteration of the global properties of structural connectivity network in schizophrenia. However, the specificity of this alteration and its possible relation with chronicity and treatment have ...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 18 February 2019Source: NeuroscienceAuthor(s): Katherine Najera, B. Matthew Fagan, Peter M. ThompsonAbstractSynaptosomal Associated Protein-25 kilodaltons (SNAP-25) is an integral member of the SNARE complex. This complex is essential for calcium-triggered synaptic vesicular fusion and release of neurotransmitters into the synaptic cleft. In addition to neurotransmission, SNAP-25 is associated with insulin release, the regulation of intracellular calcium, and neuroplasticity. Because of SNAP-25's varied and crucial biological roles, the consequences of changes in this protein can be seen ...
Source: Neuroscience - Category: Neuroscience Source Type: research
Yongfeng Yang, Shu Liu, Xiaoyan Jiang, Hongyan Yu, Shuang Ding, Yanli Lu, Wenqiang Li, Hongxing Zhang, Bing Liu, Yue Cui, Lingzhong Fan, Tianzi Jiang, Luxian Lv
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Contributors : Jocelynn R Pearl ; Seth A AmentSeries Type : Expression profiling by arrayOrganism : Homo sapiensTranscriptional regulatory changes in the developing and adult brain are prominent features of brain diseases, but the involvement of specific transcription factors (TFs) remains poorly understood. We integrated brain-specific DNase footprinting and TF-gene co-expression to reconstruct a transcriptional regulatory network (TRN) model for the human brain. We identified key regulator TFs whose predicted target genes were enriched for differentially expressed genes in the prefrontal cortex of individuals with psychi...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
 Panic attacks have a way of popping up at the most inconvenient times – like when you are recording a podcast. In this episode, Gabe has a panic attack in front of the microphone and decides that the silver lining is showing listeners that even someone in recovery has symptoms. Listen in to this episode to learn about panic attacks and see if Gabe makes it out okay. (Spoiler alert: He’s fine.) SUBSCRIBE &REVIEW “We call ourselves recovered, but these symptoms don’t entirely go away.” – Michelle Hammer   Highlights From ‘Panic Attack Live’ Episode [2:30]...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: A Bipolar, A Schizophrenic, and a Podcast Anxiety and Panic Source Type: blogs
Discussion Bipolar disorder (BD) is a chronic, recurrent, affective disorder with fluctuations in energy and mood. “Bipolar disorder, previously known as manic depressive illness, is a severe chronic mood disorder characterized by episodes [note not just one instance] of mania, hypomania, and alternating or intertwining episodes of depression.” Affective disorders are classified based on their severity and extent, from unipolar to BDII to BDI. “Individuals with unipolar disorder present with depressive episodes only, and those with bipolar II or I disorder show increasingly pronounced episodes of mood ele...
Source: - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
CONCLUSIONS: These results suggest that ER-disturbances in SZ are characterized by an inefficient initialization and failure to sustain regulatory control, whereas in BD, a failure to recruit regulatory resources may represent initial deficits in formulating adequate representations of the regulatory needs. This may help to further understand how ER-disturbances give rise to symptomatology of BD and SZ. PMID: 30773147 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
When we hear someone is psychotic, we automatically think of psychopaths and cold-blooded criminals. We automatically think “Oh wow, they’re really crazy!” And we automatically think of plenty of other myths and misconceptions that only further the stigma surrounding psychosis. In other words, the reality is that we get psychosis very wrong. For starters, psychosis consists of hallucinations and/or delusions. “You can have one or both at the same time,” said Devon MacDermott, Ph.D, a psychologist who previously worked in psychiatric hospitals and outpatient centers, treating individuals experi...
Source: Psych Central - Category: Psychiatry Authors: Tags: Disorders General Schizophrenia Stigma Hallucinations Hearing Voices Psychosis Psychotic Episode serious mental illness Source Type: news
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