Tbx6 revealed as crucial to heart and skeleton formation from stem cells

(University of Tsukuba) In a study of over 50 transcription factors, Tbx6 alone was able to stimulate mesoderm formation in laboratory-grown stem cells, and could cause those stem cells to become cardiovascular or musculoskeletal cells; the University of Tsukuba-led research team found that this essential role of Tbx6 in mesoderm and cardiovascular speci?cation is conserved from lower organisms to mammals. This research report validated a new direct reprogramming-based approach that may enhance future regenerative medicine research.
Source: EurekAlert! - Biology - Category: Biology Source Type: news