Sleep Disturbances Are Commonly Reported Among Patients Presenting to a Gastroenterology Clinic
ConclusionsPatients presenting to a tertiary care GI clinic report poorer sleep than healthy controls. In general, patients with IBS report the highest rates of sleep difficulties compared to patients with other diagnoses.
Authors: Heiser C, Eckert D Abstract The prevalence of obstructive sleep apnea (OSA) is considered to be very high in western industrialized countries. There are conservative and surgical forms of treatment for OSA; however, the pathophysiology is largely unexplained and cannot be explained by anatomical abnormalities alone. In recent years, a number of non-anatomical factors have been found that favor the development of OSA. These include the respiratory excitation threshold (arousals), the respiratory drive (loop gain), as well as the control and function of the muscular upper airway dilators. The understand...
Inflammatory Bowel Disease
Publication date: Available online 22 August 2019Source: Academic PediatricsAuthor(s): Irene Kocolas, Wendy Hobson, Ameet Daftary, Marta King, James F. Bale
No abstract available
ConclusionsMulti-method assessment is vital in understanding sleep problems in children with ASD. Broad estimates of quantity of sleep do not necessarily describe the difficulties experienced. Using questionnaires in addition to objective measurement may be a means to understand sleep problems in children with ASD and to an improved understanding of their impact.
Dysphagia is one of the most common postoperative symptoms reported by patients following antireflux surgery. A recent paper in Clinical Gastroenterology and Hepatology provided a comprehensive overview of recent advances in the management of esophageal motility disorders in general.1 In this issue, Hasak and colleagues2 report outcomes of adults who developed dysphagia following antireflux surgery for treatment of gastroesophageal reflux disease. Of 157 patients, 64.3% reported postoperative dysphagia; about half reported clinically significant dysphagia, defined as a score ≥ 2 on a 5-point Likert scale.
Authors: Kim S, Kang Y, Park S, Koh H, Kim S Abstract BACKGROUND: It has been known that vitamin D level (serum 25[OH]D) has correlation with inflammatory bowel disease (IBD). The purpose of this study is to investigate changes of serum 25[OH]D in pediatric IBD patients according to the disease activity. METHODS: A total of 96 children and adolescent with IBD were enrolled in this retrospective study. Serologic inflammatory markers and clinical disease activity scores of the patients were collected, and their correlations with serum 25[OH]D were analyzed. Seasonal variations of serum 25[OH]D were also investiga...
ConclusionsThe analyses showed that Hb was safe to use during periods of SR or PSD, acting as an adaptogen for these situations, in addition to being able to reduce cholinesterase activity, which suggests its neuroprotective action. In relation to the estrous cycle, Hb can act as a protector in SR situations.Graphical abstract
ConclusionsTaking into consideration the central role of inflammation in the pathophysiology of CRC and the recognised connection between inflammatory events and cancer, these results enlighten the relevance of the phenolic constituents of pennyroyal as important pharmacological sources in the investigation of new treatment options for patients with inflammatory bowel diseases.Graphical abstract
Publication date: 21 August 2019Source: Neuron, Volume 103, Issue 4Author(s): Matthew P. WalkerWe are suffering a global sleep-loss epidemic. The health consequences within an individual are well characterized. But does society suffer just as much? Here, I discuss how insufficient sleep erodes our societal fabric as much as it does our biological fabric, and offer some prescriptive remedies.