There ’s New Hope For Preventing Alzheimer’s — And It Could Be Within Your Control

Margaret Daffodil Graham tries to live a healthy life, particularly since she has a health issue that requires constant attention. Like more than 100 million other Americans, the 74-year-old from Winston-Salem, N.C., has high blood pressure, and she has been taking medication to control it since she was in her 30s. So when she read that her nearby hospital, Wake Forest Baptist Medical Center, was looking for people with hypertension to volunteer for a study, she quickly signed up, knowing the doctors would monitor her blood pressure more intensively and hopefully lower her risk of developing heart disease and stroke. What Graham didn’t realize was that by joining the trial, she wouldn’t just be benefiting her heart. The study, called SPRINT MIND, was designed to test whether aggressively lowering blood pressure would have an effect on people’s risk of cognitive decline, including symptoms of dementia related to Alzheimer’s disease. Indeed, the trial’s results are now the first solid confirmation that lowering blood pressure reduces the risk of both mild cognitive impairment (MCI), a degree of brain decline that’s considered the gateway to dementia, and probable dementia. It was a revelation to Graham as well as others who volunteered. “It never occurred to me that controlling my blood pressure could protect me from dementia,” says Arthur Lane, 89, another participant in the study. “I think this is wonderful.” Some 1...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Aging Alzheimer's Research Source Type: news

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Conclusions:In a middle-aged population-based cohort, the prevalence of a RERA index≥ 5 events/h was low (3.8%) and was not associated with negative clinical outcomes when using the currently recommended scoring criteria of the American Academy of Sleep Medicine.Citation:Ogna A, Tobback N, Andries D, Preisig M, Vollenweider P, Waeber G, Marques-Vidal P, Rubio JH, Heinzer R. Prevalence and clinical significance of respiratory effort-related arousals in the general population.J Clin Sleep Med. 2018;14(8):1339–1345.
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
Conclusions:DORAs offer an additional treatment option for insomnia. More clinical trials are needed to robustly evaluate their safety and effectiveness in several subclasses of individuals with insomnia. Given the published literature, head-to-head comparisons to existing treatment for insomnia are warranted.Citation:Janto K, Prichard JR, Pusalavidyasagar S. An update on dual orexin receptor antagonists and their potential role in insomnia therapeutics.J Clin Sleep Med. 2018;14(8):1399–1408.
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
Patients with rheumatoid arthritis who have had cancer can, in general, be treated with tumor necrosis factor inhibitors without increasing cancer recurrence risk, new data showed.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Abstract PURPOSE: The occurrence of upper extremity lymphedema after regional nodal irradiation (RNI) for breast cancer treatment varies significantly based on patient and treatment factors. The relationship between the radiation therapy (RT) field design and lymphedema risk is not well-characterized. The present study sought to correlate the variations in RT field design with lymphedema outcomes. METHODS AND MATERIALS: Women with stage II-IV breast cancer receiving RNI after breast surgery that included sentinel lymph node biopsy or axillary dissection were identified. Their arm circumference was measured be...
Source: Ann Oncol - Category: Cancer & Oncology Authors: Tags: Int J Radiat Oncol Biol Phys Source Type: research
Dr Ruth Webster, of the George Institute for Global Health in Australia, said: 'Our results could help millions of people globally reduce their blood pressure and their risk of heart attack or stroke.'
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Authors: Alexander W Abstract We review key findings in the areas of prostate cancer, non-small-cell lung cancer, breast cancer, esophageal cancer, pancreatic cancer, leukemias, metastatic colon cancer, and one session on molecular profiling guidance of therapy. PMID: 30100691 [PubMed]
Source: P and T - Category: Drugs & Pharmacology Tags: P T Source Type: research
Margaret Daffodil Graham tries to live a healthy life, particularly since she has a health issue that requires constant attention. Like more than 100 million other Americans, the 74-year-old from Winston-Salem, N.C., has high blood pressure, and she has been taking medication to control it since she was in her 30s. So when she read that her nearby hospital, Wake Forest Baptist Medical Center, was looking for people with hypertension to volunteer for a study, she quickly signed up, knowing the doctors would monitor her blood pressure more intensively and hopefully lower her risk of developing heart disease and stroke. What...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Aging Alzheimer's Research Source Type: news
Margaret Daffodil Graham tries to live a healthy life, particularly since she has a health issue that requires constant attention. Like more than 100 million other Americans, the 74-year-old from Winston-Salem, N.C., has high blood pressure, and she has been taking medication to control it since she was in her 30s. So when she read that her nearby hospital, Wake Forest Baptist Medical Center, was looking for people with hypertension to volunteer for a study, she quickly signed up, knowing the doctors would monitor her blood pressure more intensively and hopefully lower her risk of developing heart disease and stroke. What...
Source: TIME: Science - Category: Science Authors: Tags: Uncategorized Aging Alzheimer's Research Source Type: news
Most people are familiar with the steps they can take to lower their risk of heart disease and cancer. Choosing your diet carefully, exercising and quitting smoking have all been shown to lower the risk of these diseases. But when it comes to dementia — including dementia related to Alzheimer’s disease — scientists haven’t found many actionable steps that people can take to lower their risk. Genes play a prominent role in who develops dementia, especially Alzheimer’s, and age is also a dominant factor in the degenerative brain disorder, but neither are under human control. Now, in a presentati...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Brain healthytime Source Type: news
In conclusion, documentation is important, a critical part of advocacy and the development process at the larger scale. It isn't just words, but rather a vital structural flow of information from one part of the larger community to another, necessary to sustain progress in any complex field. We would all do well to remember this - and to see that building this documentation is an activity in which we can all pitch in to help. Evidence Suggests that, at Least in Earlier Stages, Alzheimer's Disease Blocks Rather than Destroys Memories https://www.fightaging.org/archives/2017/07/evidence-suggests-that-at-least-in-ea...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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