Adverse effects of chemotherapy on the teeth and surrounding tissues of children with cancer: A systematic review with meta-analysis

Considerable improvements have been seen during the last decades in the development of effective treatment protocols for childhood cancer, which usually consist of multiagent chemotherapy (CH), radiotherapy, or a combination of both. For example, the cure rate for Acute Lymphoblastic Leukemia (ALL), which is the most common childhood malignancy [1], has increased from less than 30% during the 1960s to an 80 –86% 5-year overall survival [2].

Source: Oral Oncology - June 12, 2018 Category: Cancer & Oncology Authors: Dan Mike Busenhart, Juliane Erb, Georgios Rigakos, Theodore Eliades, Spyridon N. Papageorgiou Tags: Review Source Type: research