Nomogram for preoperative prediction of nodal extracapsular extension or positive surgical margins in oropharyngeal squamous cell carcinoma

The management of oropharyngeal squamous cell carcinoma (OPSCC) has undergone a significant transformation over the last two decades, reflecting the increasing incidence of human papillomavirus (HPV) that some experts have called an epidemic [1]. Patients with HPV-associated OPSCC are primarily younger, healthier individuals with little or no tobacco exposure [2]. They tend to have increased response to treatment compared to patients with OPSCC associated with tobacco and alcohol use and thus have much better oncologic outcomes [2,3].

Source: Oral Oncology - June 13, 2018 Category: Cancer & Oncology Authors: Mohammad K. Hararah, William A. Stokes, Bernard L. Jones, Ayman Oweida, Ding Ding, Jessica McDermott, Julie Goddard, Sana D. Karam Source Type: research