Oncogenic drivers in 11q13 associated with prognosis and response to therapy in advanced oropharyngeal carcinomas

In the last decades, several epidemiological studies have revealed decreased incidence of head and neck squamous cell carcinomas (HNSCC) in oral cavity and larynx as a consequence of lower exposure to the tobacco products. Nevertheless, an increasing incidence of oropharyngeal squamous cell carcinomas (OPSCC) mainly associated with oncogenic human papillomavirus (HPV) has been reported [1 –6].

Source: Oral Oncology - June 15, 2018 Category: Cancer & Oncology Authors: M.C. Barros-Filho, L.A. Reis-Rosa, M. Hatakeyama, F.A. Marchi, T. Chulam, C. Scapulatempo-Neto, U.R. Nicolau, A.L. Carvalho, C.A.L. Pinto, S.A. Drigo, L.P. Kowalski, S.R. Rogatto Source Type: research