Home-based Exercise in Chronic Kidney Disease

Conditions:   Chronic Kidney Disease;   End-stage Renal Disease Intervention:   Other: Home-based exercise Sponsors:   Cardenal Herrera University;   Consorci Sanitari de Terrassa. Hospital de Terrassa Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Authors: Klug E, Raal FJ, Marais AD, Smuts CM, Schamroth C, Jankelow D, Blom DJ, Webb DA Abstract South Africa (SA) is home to a heterogeneous population with a wide range of cardiovascular risk factors. Cholesterol reduction in combination with aggressive management of modifiable risk factors, including nutrition, physical activity, blood pressure and smoking, can help to reduce and prevent morbidity and mortality in individuals who are at increased risk of cardiovascular events. This updated consensus guide to management of dyslipidaemia in SA is based on the updated European Society of Cardiology and European At...
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research
Conclusions: In CKD patients, the use of second-generation DES was associated with lower risk of long-term all-cause mortality, in stent restenosis and stent thrombosis as compared with first-generation DES. No differences were found regarding repeat revascularization, MI, and MACE. PMID: 30422052 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
We examined 717 patients with severe AS and HF undergoing TAVI. NT-proBNP nonresponders were defined as patients whose NT-proBNP levels decreased by  ≤ 30%. Mean NT-proBNP levels decreased from 7698 ± 7853 pg/mL (baseline) to 4523 ±  5173 pg/mL (post-TAVI); 269 patients (38%) were nonresponders. Female gender and prevalence of diabetes mellitus (DM), chronic kidney disease (CKD), atrial fibrillation (AF), and history of coronary artery revascularization were more common for NT-proBNP nonresponders. Permanent pacemaker implantation rate was higher for N...
Source: Heart and Vessels - Category: Cardiology Source Type: research
AbstractBackgroundStudies in the use of the calcimimetic, cinacalcet, in pediatric chronic kidney disease (CKD) are few and limited to older children with secondary hyperparathyroidism (sHPT), a major morbid complication contributing to poor growth, bone deformities, and cardiovascular disease. Our objectives were to determine a safe and effective dosing regimen of cinacalcet in the treatment of infants and young children with sHPT that was refractory to standard care and to examine their growth during treatment.MethodsTen young pediatric patients with advanced CKD were studied retrospectively during 11 courses of treatmen...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
ConclusionsIn conclusion, a single 0.25  mg/kg dose of cinacalcet was evaluated to be a safe starting dose in these children aged
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
AbstractLife expectancy in patients with all stages of chronic kidney disease (CKD) falls far short of that in the general population. Cardiovascular disease is the leading cause of mortality in pediatric patients with CKD. In contrast to the intimal atherosclerotic lesions that characterize cardiovascular disease in the general population, vascular endothelial dysfunction, medial arterial calcification, and cardiac dysfunction contribute to cardiovascular pathological conditions in CKD. The pathogenesis of these lesions, the origins of which can be identified in the absence of traditional cardiovascular risk factors, is i...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
This study aimed to determine if using additional measures improves the accurate identification of nonadherence beyond provider assessment alone.MethodsEighty-seven adolescents and young adults (AYAs), age 11 –19 years, with chronic kidney disease (CKD) [stage 1–5/end-stage renal disease (ESRD)] and prescribed antihypertensive medication, their caregivers, and 17 medical providers participated in the multisite study. Five adherence measures were obtained: provider report, AYA report, caregiver repo rt, electronic medication monitoring (MEMS), and pharmacy refill data [medication possession ratio (MPR)...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
ConclusionsThe BTP and B2M equations are the worst performing of the eGFR-EPI equations, and no benefit is observed with the addition of BTP or B2M to Cr/cysC.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
The Journal of Clinical Hypertension, EarlyView.
Source: The Journal of Clinical Hypertension - Category: Cardiology Authors: Tags: COMMENTARY Source Type: research
We used electronic health records (EHRs) data from 5658 ambulatory chronic kidney disease (CKD) patients with hypertension and prescribed antihypertensive therapy to examine antihypertensive drug prescribing patterns, blood pressure (BP) control, and risk factors for resistant hypertension (RHTN) in a real ‐world setting. Two‐thirds of CKD patients and three‐fourths of those with proteinuria were prescribed guideline‐recommended renoprotective agents including an angiotensin‐converting enzyme inhibitor (ACEI) or an angiotensin receptor blocker (ARB); however, one‐third were not prescribed an ACEI or ARB. CKD pa...
Source: The Journal of Clinical Hypertension - Category: Cardiology Authors: Tags: ORIGINAL PAPER Source Type: research
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