Genetic and transcriptional evolution alters cancer cell line drug response

Genetic and transcriptional evolution alters cancer cell line drug responseGenetic and transcriptional evolution alters cancer cell line drug response, Published online: 08 August 2018; doi:10.1038/s41586-018-0409-3The extent, origins and consequences of genetic variation within human cell lines are studied, providing a framework for researchers to measure such variation in efforts to support maximally reproducible cancer research.

Source: Nature AOP - August 8, 2018 Category: Research Authors: Uri Ben-David Benjamin Siranosian Gavin Ha Helen Tang Yaara Oren Kunihiko Hinohara Craig A. Strathdee Joshua Dempster Nicholas J. Lyons Robert Burns Anwesha Nag Guillaume Kugener Beth Cimini Peter Tsvetkov Yosef E. Maruvka Ryan O ’Rourke Anthony Garrity Source Type: research