Electrostatic lock in the transport cycle of the multidrug resistance transporter EmrE [Biophysics and Computational Biology]

EmrE is a small, homodimeric membrane transporter that exploits the established electrochemical proton gradient across the Escherichia coli inner membrane to export toxic polyaromatic cations, prototypical of the wider small-multidrug resistance transporter family. While prior studies have established many fundamental aspects of the specificity and rate of substrate transport in...

http://www.pnas.org/content/115/32/E7502.short?rss=1

Source: Proceedings of the National Academy of Sciences - August 7, 2018 Category: Science Authors: Josh V. Vermaas, Susan B. Rempe, Emad Tajkhorshid Tags: PNAS Plus Source Type: research