The role of the platelet mass index as a new prognostic factor in Fournier’s Gangrene

ConclusionLow PMI levels might be an important parameter for a worse FG prognosis. Monitoring the PMI levels might therefore have prognostic and therapeutic implications, as high UFGSI scores and low Mg levels could be associated with a worse prognosis in patients with FG.
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research

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CONCLUSIONS: HBOT and surgical debridement are independent predictors of reduced FG related mortality. PMID: 32083420 [PubMed - as supplied by publisher]
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
ConclusionDespite the recognized severity of Fournier’s Syndrome, early diagnosis combined with extensive surgical debridement, broad-spectrum antibiotic therapy and measures and oxygen therapy when available are important measures to contain the rapid progression of the disease, thus decreasing its levels of mortality.ResumoIntroduçãoA Gangrena de Fournier é uma infecção polimicrobiana ocasionada por microrganismos aeróbios e anaeróbios, que determinam uma fascite necrosante rápida e progressiva, comprometendo principalmente a região do períneo e ...
Source: Journal of Coloproctology - Category: Gastroenterology Source Type: research
Purpose of review Necrotizing pneumonia is a severe form of community-acquired pneumonia characterized by rapid progression of consolidation to necrosis and cavitation which may lead to pulmonary gangrene. Morbidity and mortality are high and chronic sequelae are frequent. The lack of guidance supports the review of the latest recommendations in the management of these pneumonias. Recent findings Antibiotic therapy alone may not be enough to alter the course of the infection, and regimens, adjunctive therapies like intravenous immunoglobulins, surgery may be required to alter the course of the disease especially with ...
Source: Current Opinion in Pulmonary Medicine - Category: Respiratory Medicine Tags: INFECTIOUS DISEASES: Edited by Michael S. Niederman and Alimuddin Zumla Source Type: research
​BY DILEM POLAT &KHALID MALIK, MDA 50-year-old man with hypertension presented to the emergency department with an exacerbation of his lower back and perianal pain that he had had for two weeks, with a new onset of active fecal draining and difficulty urinating for four hours. He said he had no headache, nausea, vomiting, weakness, fatigue, fever, and chills, and all other reviews of systems were negative.His temperature was 98.5°F, blood pressure was 108/57 mm Hg, pulse rate was 113 bpm, respiratory rate was 20 bpm, and oxygen saturation was 97% on room air. His abdomen was soft, mildly distended, and not tender...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
CONCLUSIONS: To the best of the authors' knowledge, this is the largest case series reported in the literature using skin and soft tissue sparing surgery for wound closure of a FG NSTI. PMID: 30299266 [PubMed - in process]
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research
ConclusionLow PMI levels might be an important parameter for a worse FG prognosis. Monitoring the PMI levels might therefore have prognostic and therapeutic implications, as high UFGSI scores and low Mg levels could be associated with a worse prognosis in patients with FG.
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research
CONCLUSIONS: Fournier's gangrene is a surgical emergency, and the main cornerstones of treatment are patient resuscitation, broad-spectrum parenteral antibiotic therapy, and, most importantly, surgical debridement. Any delay in treatment can dramatically increase mortality. PMID: 30059341 [PubMed - in process]
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research
Background: Fornier gangrene is an extremely rare disease of the genitals. This disease is a result of the urogenital tract, anorectal area, and genital skin infections, appearing usually in immunocompromised patients with diabetes, obesity, and malignant neoplasms. The basic treatment of Fournier gangrene includes an emergency surgical intervention combined with antibiotic therapy and detoxification.Methods: A review of recent papers comprising studies and reviews published in 2005 –2016 was performed. The clinical cases were studied at the Department of Purulent Surgery Central Clinical Hospital No. 1, where 7 pati...
Source: Urologia Internationalis - Category: Urology & Nephrology Source Type: research
ConclusionsThe mainstay of treatment for Fournier ’s gangrene should include fluid resuscitation, broad-spectrum antibiotic therapy, intensive care, nutritional support, and early aggressive surgical debridement of all necrotic tissue.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
CONCLUSIONS Favorable outcome of FG treatment with low morbidity and no mortality can be achieved with rapid diagnosis, urgent surgical debridement of all necrotic tissues, and broad-spectrum empirical antimicrobial therapy, usually with combined antibiotics, against aerobic and anaerobic bacteria. Prevention of uroseptic shock by treating localized infection is compulsory. PMID: 29374769 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
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