Effect of Helicobacter pylori Infection on GATA - 5 and TFF1 Regulation, Comparison Between Pediatric and Adult Patients

ConclusionsOur results suggest that the upregulation ofGATA-5 andTFF1 observed in vitro and in vivo may be correlated with a protective effect of the mucosa in response to infection. The epigenetic inactivation ofGATA-5 observed in human biopsies from infected patients may suggest that this alteration is an early event occurring in association withH. pylori infection.
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research