Relapse in the first three months postpartum in women with history of serious mental illness

Relapse of serious mental illness (psychotic and bipolar disorders; SMI) in the postpartum period is potentially devastating for mother and baby. There is limited evidence on whether medication in the perinatal period is protective against postpartum relapse for women with SMI particularly non-affective psychoses. We aimed to investigate risk factors for postpartum relapse, particularly the potential prophylactic effects of medication.
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research

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Publication date: Available online 16 October 2018Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Yan Zhao, Xiao Liang, Feng Zhu, Yan Wen, Jiawen Xu, Jian Yang, Miao Ding, Bolun Cheng, Mei Ma, Lu Zhang, Shiqiang Cheng, Cuiyan Wu, Sen Wang, Xi Wang, Yujie Ning, Xiong Guo, Feng ZhangAbstractAttention deficit hyperactivity disorder (ADHD), bipolar disorder (BP) and schizophrenia (SCZ) are complex psychiatric disorders. We conducted a large-scale integrative analysis of genome-wide association studies (GWAS) and life course consistent methylation quantitative trait loci (meQTLs) datasets. The GWAS data of ADHD (inclu...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Borderline personality disorder (BPD) has a wide range of symptoms and clinical features that overlap with other diagnostic categories. Diagnosis is important because different disorders respond to different forms of treatment. Differential diagnosis is particularly relevant for distinguishing BPD from bipolar spectrum disorders, requiring a careful evaluation of affective instability and hypomania. BPD may also be confused with major depression, schizophrenia, attention-deficit/hyperactivity disorder, and posttraumatic stress disorder.
Source: The Psychiatric Clinics of North America - Category: Psychiatry Authors: Source Type: research
ConclusionsThe findings suggest that the stigma associated with parenting a child with disabilities may be one mechanism that places such parents at risk for poor health. Efforts to alleviate the stigma associated with developmental disorders or mental health problems may have beneficial effects on health of parents of individuals with such conditions.
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
 Depression is an inconsiderate illness. It doesn’t care whether you have nothing going on or a lot going on. It will strike whenever it feels like it. Depression doesn’t care if you have a home filled with people, family obligations, or even a podcast to record. If this symptom of mental illness wants out, it’s coming out. In this episode of A Bipolar, a Schizophrenic, and a Podcast, our hosts attempt to record an episode, but Gabe breaks down and confides to Michelle that he isn’t doing well. The recorder was running and Gabe’s attempt at faking it until he makes it backfired. However, a...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: A Bipolar, A Schizophrenic, and a Podcast Depression Source Type: blogs
Publication date: Available online 10 October 2018Source: Journal of Psychiatric ResearchAuthor(s): Shufen Li, Qiong Yang, Yu Hou, Tingyun Jiang, Lu Zong, Zhongju Wang, Xia Luo, Wenquan Liang, Hu Zhao, Yuping Ning, Cunyou ZhaoAbstractSchizophrenia (SCZ) and bipolar disorder (BPD) are severe mental illnesses with evidence of significant genetic and environmental etiological elements in their complex etiologies. 5‘-Methylcytosine is the main epigenetic DNA modification that mediates the interplay between genetic and environmental components. In humans, most 5‘-methylcytosine modifications are observed in CpG-rich...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
The Research Domain Criteria (RDoC) scheme has guided the research agenda of the National Institute of Mental Health for the past decade. The essence of RDoC is its dimensional conception of mental illness, with the assumption that psychopathology is a manifestation of extremes along axes of neuropsychological variation. Research, it follows, should emphasize normal neuropsychological function and its associated neurocircuitry. We argue that RDoC, dressed in terms of modern neurobiology, is in fact a return to the humoral theory of Galen, a dimensional approach in which physical and mental health requires a balance of the ...
Source: Molecular Neuropsychiatry - Category: Neuroscience Source Type: research
   Blue is for boys and pink is for girls, right? That depends on what generation you live in. Today, many people disregard such silly color assignments, or at least go for “gender neutral” colors. But a hundred years ago, all the top fashionistas insisted that pink was a masculine color and blue was feminine. Masculinity has long had an identity complex. How much “girly” stuff can a man enjoy without being viewed as non-masculine? Women have redefined femininity, so why can’t men redefine what it means to be masculine? Listen to this week’s episode and you might begin to underst...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Men's Issues The Psych Central Show Women's Issues Gabe Howard Masculinity Psych Central Show Podcast Vincent M. Wales Source Type: blogs
Individuals with serious mental illness (SMI) such as schizophrenia and bipolar disorder face a higher risk of early death due to cardiovascular disease and other preventable chronic illnesses. Young adulthood is a critical window of development for lifestyle interventions to improve the long-term health and quality of life in this population. Fit Forward is an NIH-funded randomized clinical trial examining the effectiveness of a group lifestyle intervention (PeerFIT) enhanced with mobile health technology compared to one-on-one mobile lifestyle coaching with Basic Education in fitness and nutrition supported by a wearable...
Source: Contemporary Clinical Trials - Category: Radiology Authors: Source Type: research
Publication date: Available online 9 October 2018Source: NeuroImage: ClinicalAuthor(s): Siri Ranlund, Maria Joao Rosa, Simone de Jong, James H. Cole, Marinos Kyriakopoulos, Cynthia H.Y. Fu, Mitul A. Mehta, Danai DimaAbstractPsychiatric illnesses are complex and polygenic. They are associated with widespread alterations in the brain, which are partly influenced by genetic factors. There have been some attempts to relate polygenic risk scores (PRS) – a measure of the overall genetic risk an individual carries for a disorder – to brain structure using univariate methods. However, PRS are likely associated with dis...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Many lines of evidence from different laboratories are now joining the same chorus: that conventional psychiatric diagnoses of serious mental illness (SMI), when tested, do not show a common biology. The article by Wolfers et al notes that SMI diagnoses do not have strong biomarkers similar to those that are already increasingly valued in the rest of medicine and that could help define disease groups, select treatments, and mark clinical outcomes. The authors used innovative regional brain structure mapping on an individual basis in people with schizophrenia and bipolar disorder and developed voxel-by-voxel measures of ind...
Source: JAMA Psychiatry - Category: Psychiatry Source Type: research
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