Clinical, Pathological, and Molecular Characteristics of CpG Island Methylator Phenotype in Colorectal Cancer: A Systematic Review and Meta-analysis.

CONCLUSION: The meta-analysis highlights key features distinguishing CIMP in colorectal cancer, including molecular characteristics of an active immune response. Improved understanding of this unique molecular subtype of colorectal cancer may provide insights into prevention and treatment.
PMID: 30071442 [PubMed - as supplied by publisher]

Source: Translational Oncology - July 30, 2018 Category: Cancer & Oncology Authors: Advani SM, Advani P, DeSantis SM, Brown D, VonVille HM, Lam M, Loree JM, Sarshekeh AM, Bressler J, Lopez DS, Daniel CR, Swartz MD, Kopetz S Tags: Transl Oncol Source Type: research