A randomized feasibility trial of clonidine to reduce perioperative cardiac risk in patients on chronic beta-blockade: the EPIC study

Conclusion This pilot randomized trial confirmed the feasibility, safety, and tolerability of a full-scale trial of oral and transdermal clonidine for reducing the risk of cardiac complications during non-cardiac surgery. This trial was registered at www.clinicaltrials.gov: NCT00335582.

http://link.springer.com/10.1007/s12630-014-0226-6

Source: Canadian Journal of Anesthesia - October 11, 2014 Category: Anesthesiology Source Type: research